Doxycycline and prednisone together

A total of 446 drugs are known to interact with Benadryl . Benadryl is in the following drug classes: anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics . Benadryl is used to treat the following conditions: Allergic Reactions. Allergic Rhinitis.

Doxycycline and prednisone together. Doxycycline (Oracea) is used only to treat pimples and bumps caused by rosacea. Doxycycline is in a class of medications called tetracycline antibiotics. It works to treat infections by preventing the growth and spread of bacteria. It works to treat acne by killing the bacteria that infects pores and decreasing a certain natural oily substance ...

The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Losartan potassium together. It is created by eHealthMe based on data from the FDA, and is updated regularly. ... Doxycycline and Prednisone: 7,485 reports; Doxycycline and Omeprazole: 6,202 reports; Doxycycline and Aspirin: 6,124 reports;

Apalutamide. Prednisolone is predicted to cause hypokalaemia (potentially increasing the risk of torsade de pointes) when given with Apalutamide. Manufacturer makes no recommendation. Severity: Severe. Evidence: Theoretical. Apalutamide is predicted to decrease the exposure to Prednisolone.Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In …Stelara Interactions. There are 457 drugs known to interact with Stelara (ustekinumab), along with 5 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 44 are major, 406 are moderate, and 7 are minor.Drug interactions are reported among people who take Doxycycline and Benadryl. Common interactions include diarrhoea among females, and chronic kidney disease among males. The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Benadryl together. It is created by eHealthMe based on 1,374 reports from ...Digoxin -- It is important that normal levels of magnesium be maintained while taking digoxin (Lanoxin) because low blood levels of magnesium can increase adverse effects from this drug, including heart palpitations and nausea. In addition, digoxin can lead to increased loss of magnesium in the urine. A health care provider will follow ...

doxycycline calcium carbonate. Applies to: doxycycline and Tums Regular Strength (calcium carbonate) Doxycycline and calcium carbonate should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of doxycycline into the bloodstream and reduce its ... Some patients do use both. However, speak to your doctor about the proper protocol for using both together. You may need additional medications and monitoring for acid production, and a few other considerations.Pediatric. Doxycycline may cause permanent discoloration of the teeth and slow down the growth of bones. This medicine should not be given to children 8 years of age and younger (except for the treatment of exposure to inhalational anthrax or rickettsia infection), unless directed by the child's doctor.Doxycycline oral tablet is available as both a generic and brand-name drug. Brand names: Acticlate, Doryx, Doryx MPC. Doxycycline comes in three oral forms: a tablet, a capsule, and a suspension.Donation. 15 Days Left. Prednisone is widely used to reduce inflammation in various conditions. It works by suppressing the immune response and reducing the production of inflammatory substances in the body. Prednisone can effectively manage inflammation associated with autoimmune diseases, allergies, and certain respiratory conditions.Mometasone Interactions. There are 78 drugs known to interact with mometasone, along with 1 disease interaction. Of the total drug interactions, 10 are major, 54 are moderate, and 14 are minor.

The American Thoracic Society (ATS) and the Infectious Diseases Society of America (IDSA) recently updated their recommendations on the diagnosis and treatment of community-acquired pneumonia (CAP ...The phase IV clinical study analyzes what interactions people have when they take Sudafed 12 hour and Doxycycline together. It is created by eHealthMe based on data from the FDA, and is updated regularly. ... Doxycycline and Prednisone: 7,485 reports; Doxycycline and Omeprazole: 6,202 reports; Doxycycline and Aspirin: 6,124 reports;Epidural use of bupivacaine (Marcaine), lidocaine (Xylocaine), morphine, fentanyl (Sublimaze) and sufentanil (Sufenta) is generally safe in breast-feeding mothers. 8, 15, 16 Morphine, codeine and ...Always consult your healthcare provider before starting or stopping any medication. Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. Minimally clinically significant. Minimize risk; assess ...Medically Reviewed. Can You Take Steroids and Antibiotics Together? Research suggests the two might work better together to fight certain infections. Here's what you need to know before...

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Iron can bind to doxycycline in the gastrointestinal tract, which may prevent their absorption into the bloodstream and possibly reduce their effectiveness. To avoid or minimize the interaction, iron-containing medications and doxycycline should preferably be taken at least three to four hours apart in most cases. Talk to your doctor if you ...doxycycline calcium carbonate. Applies to: doxycycline and Tums Regular Strength (calcium carbonate) Doxycycline and calcium carbonate should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of doxycycline into the bloodstream and reduce its ...Prednisone, a corticosteroid commonly prescribed for a wide variety of indications, is considered safe with most cough and cold medications. However, there is considered to be an interaction between prednisone and NSAIDs (non-steroidal anti-inflammatory drugs) and the use of both together is generally recommended to be avoided .I am getting dehydrated no reason. went to urgent care on feb 27 urinary tract inf. no fever. he gave me doxycycline 2 times a day i have horrible drug allergies can only take levaquin avelox penicillin cannot take sulfa or macrobid. he gave me doxycycl. 2 doctors weighed in across 2 answers.Dosages vary for all of these uses. For many species, including dogs and humans, the two drugs are interchangeable, but cats and horses absorb prednisolone better than prednisone. The FDA (U.S. Food & Drug Administration) has approved some prednisolone products for use in dogs, cats, and horses.Upgrades Wolfe Research upgraded the previous rating for Matson Inc (NYSE:MATX) from Underperform to Peer Perform. In the third quarter, Matson s... Wolfe Research upgraded the pr...

As both Ibuprofen and Prednisone are used to treat painful conditions, there are times when both of these medicines are prescribed together. In such circumstances, it is natural for the patient to wonder whether it is safe to take both these medicines together. What are the actions and side effects of both Ibuprofen and …Applies to: prednisone and metformin. PredniSONE may interfere with blood glucose control and reduce the effectiveness of metFORMIN and other diabetic medications. Monitor your blood sugar levels closely. You may need a dose adjustment of your diabetic medications during and after treatment with predniSONE. It is important to tell your …Jan 3, 2024 · Generic doxycycline is available. 3. Downsides. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: A headache, nausea, dyspepsia, joint or back pain, nasal and sinus congestion, or a rash. Xarelto disease interactions. There are 6 disease interactions with Xarelto (rivaroxaban) which include: bleeding. valvular heart disease. antiphospholipid syndrome. hepatic impairment. renal disease. unstable blood pressure.I am feeling that the prednisone was helping our dog, and not causing any stomach or intestinal problems. My sister has been on prednisone for Lupus for years, and without it, she feels miserable. I believe we should keep up the doxycycline and prednisone and perhaps test for the hepatozoonosis and start an anti-parasite medication if it is found.Cimzia disease interactions. There are 7 disease interactions with Cimzia (certolizumab) which include: infections. malignancies. neurologic reactions. tuberculosis. CHF. hematologic abnormalities. hepatitis B.When joining pieces of wood together using a carriage bolt, the square head on the bolt can become stripped in the hole, making them hard to tighten. Expert Advice On Improving You...Captain Kate McCue, the captain of Celebrity Cruises' Celebrity Edge, is something of a rock star in the cruise world. The first mistake the internet troll made was questioning a w...Hydroxyzine can safely be taken with prednisone as there is no known interaction between them. This applies to both forms of hydroxyzine available: Additionally, they don't share many common side effects. The most common side effects for hydroxyzine include: The most common side effects for prednisone include: To reduce the incidence … Buy Prednisone Online Prednisone 40, 20, 10, 5 mg $0.29 Per Pill Active Ingredient: Prednisone Prednisone is able to help during any severe disease. Prednisone is a commonly prescribed medication that belongs to a class of drugs known as corticosteroids. It is primarily used for its potent anti-inflammatory and immunosuppressive properties. Meloxicam may affect how well drugs that lower blood pressure work. Blood pressure medications like ACE inhibitors, angiotensin receptor blockers (ARBs), or beta-blockers may be less effective if taken with meloxicam (Fournier, 2012; Johnson, 1994).Meloxicam may have the same effect on other medications such as diuretics (aka "water pills"), drugs used to stop fluid retention or lower high ...

Doxycycline Dose and How to Give Doxycycline to Dogs. In general, the dose of this antibiotic for dogs is 5-10mg/kg. This dose is usually split into two and given about 12 hours apart. Of course, this dose may change based on the infection and your dog's health, so always defer to what your vet prescribes.

Indications. Doxycycline hyclate is a water-soluble tetracycline antibiotic that kills and prevents the growth of a wide range of gram-positive and -negative bacteria. It plays a role in managing and treating acne, malaria (for prophylaxis and treatment), skin infections, sexually transmitted infections (i.e., chlamydia, syphilis, gonorrhea ...Antacids commonly contain calcium, which binds doxycycline in the GI tract. If these medications are used together, neither may be absorbed properly, and the benefits of both are lost. Iron-containing vitamin supplements produce the same problem. (Iron supplements are often used concurrently with doxycycline to treat feline infectious anemia.More about Prednisone. Ratings & Reviews. Doxycycline has an average rating of 6.4 out of 10 from a total of 1629 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 26% reported a negative effect. Prednisone has an average rating of 7.6 out of 10 from a total of 851 ratings on Drugs.com. 70% of reviewers reported a ...Since prednisone does tend to cause insomnia in many individuals, over-the-counter (OTC) medications, like Benadryl, are commonly used to help sleep in the evening. Fortunately, as mentioned above, diphenhydramine is safe to use with prednisone and there are no safety issues taking both together.Prednisone, a corticosteroid commonly prescribed for a wide variety of indications, is considered safe with most cough and cold medications. However, there is considered to be an interaction between prednisone and NSAIDs (non-steroidal anti-inflammatory drugs) and the use of both together is generally recommended to be avoided .CDC Yellow Book 2024. During pretravel consultations, travel health providers must consider potential interactions between vaccines and medications, including those already taken by the traveler. A study by S. Steinlauf et al. identified potential drug-drug interactions with travel-related medications in 45% of travelers taking medications ...For the safety primary endpoint, 256 patients were needed to show a reduction from 60% to 40% in adverse reactions of grade 3 or more for those started on doxycycline compared with prednisolone, with 80% power, 5% significance, and allowing for 20% loss to follow-up at 1 year. 13, 22 When estimating the number of participants required for the ...

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Cautions with other medicines. There are some medicines that do not mix well with doxycycline. Before taking it, tell your doctor if you're already taking any of these medicines: indigestion remedies ( antacids) stomach ulcer medicines that contain bismuth such as Pepto-Bismol. other antibiotics, such as rifampicin. doxycycline calcium carbonate. Applies to: doxycycline and Tums Regular Strength (calcium carbonate) Doxycycline and calcium carbonate should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of doxycycline into the bloodstream and reduce its ... Side Effects. Nausea, vomiting, heartburn, increased appetite, weight gain, or acne may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that ... CE is closely related to RIF occurrence, and the combined oral administration of prednisone acetate and doxycycline can be a treatment option for patients with RIF with CE and improves reproductive outcomes, although it does not improve the CE cure rate compared with doxycycline treatment alone.Ventolin Interactions. There are 419 drugs known to interact with Ventolin (albuterol), along with 5 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 19 are major, 381 are moderate, and 19 are minor.STERLING CAPITAL SPECIAL OPPORTUNITIES FUND CLASS R6- Performance charts including intraday, historical charts and prices and keydata. Indices Commodities Currencies StocksDoxycycline can also be used to prevent malaria and treat infections caused by mites, ticks, or lice. Doxycycline hyclate and doxycycline monohydrate are two different salt forms of doxycycline available; one difference between the two is that doxycycline hyclate is soluble in water, while doxycycline monohydrate is very slightly soluble in water.The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Hydrochlorothiazide together. It is created by eHealthMe based on data from the FDA, and is updated regularly. ... Doxycycline and Prednisone: 7,485 reports; Doxycycline and Omeprazole: 6,202 reports; Doxycycline and Aspirin: 6,124 reports;Sep 15, 2009 · Answers. Prilosec isn't considered an antacid in this case. Tetracycline antibiotics, including doxycycline, often come with a warning that states "do not take iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking... It is the polyvalent ions (iron, calcium, magnesium, zinc, aluminum ... Summary: Drug interactions are reported among people who take Prednisone and Mucinex. Common interactions among females include bronchitis and chronic obstructive pulmonary disease. Common interactions among males include dyspnoea and pneumonia. The phase IV clinical study analyzes what interactions people have when they take Prednisone and ... ….

More about Prednisone. Ratings & Reviews. Doxycycline has an average rating of 6.4 out of 10 from a total of 1629 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 26% reported a negative effect. Prednisone has an average rating of 7.6 out of 10 from a total of 851 ratings on Drugs.com. 70% of reviewers reported a ...Abstaining from drinking alcohol while on prednisone treatment is always the best option. Excessive and regular alcohol consumption is not recommended. Prednisone is a corticosteroid, and it is used to reduce inflammation or suppress the immune system. It is used to treat many different diseases, and the range of dosing is wide.prednisone, amoxicillin, doxycycline, ciprofloxacin, cephalexin, azithromycin, metronidazole, clindamycin, ceftriaxone, Augmentin. Images. Cefpodoxime Proxetil 200 mg (C 62) View all images. Drugs.com Mobile Apps. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication …Summary: Drug interactions are reported among people who take Mucinex and Doxycycline. Common interactions among females include diarrhoea and sinusitis. Common interactions among males include dyspnoea and pneumonia. The phase IV clinical study analyzes what interactions people have when they take Mucinex and Doxycycline together.The phase IV clinical study analyzes what interactions people have when they take Benzonatate and Doxycycline hyclate together. It is created by eHealthMe based on data from the FDA, and is updated regularly. ... Doxycycline hyclate and Prednisone: 2,663 reports; Doxycycline hyclate and Aspirin: 1,979 reports; Doxycycline hyclate and …Yes, it’s safe to take azithromycin and prednisone together. Prednisone is a common corticosteroid medication that’s available with a prescription from your healthcare provider. In fact, many situations call for both an antibiotic and a corticosteroid. This is especially true for respiratory and sinus infections.Key takeaways: Cyclobenzaprine (Amrix) is a muscle relaxant that can interact with many medications. This includes many antidepressants, sedatives, and anticholinergic medications like diphenhydramine (Benadryl). Cyclobenzaprine interactions raise the risk of side effects. These include serotonin syndrome, sleepiness, and dry mouth.The phase IV clinical study analyzes what interactions people have when they take Naproxen sodium and Doxycycline together. It is created by eHealthMe based on data from the FDA, and is updated regularly. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world.A total of 587 drugs are known to interact with prednisone . Prednisone is in the drug class glucocorticoids . Prednisone is used to treat the following conditions: Acute Lymphocytic Leukemia. Adrenocortical Insufficiency. Adrenogenital Syndrome. Allergic Reactions.Grapefruit juice can significantly increase the blood levels and effects of hydroxychloroquine, which may result in an irregular heart rate or other conduction disturbances. Talk to your doctor if you have any questions or concerns. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness ... Doxycycline and prednisone together, There are 10 disease interactions with Enbrel (etanercept) which include: hepatitis B. infections. tuberculosis. alcoholic hepatitis. heart failure. hematologic abnormalities. hypoglycemia. nervous system disorders., Use with caution:prednisone (1), deflazacort (1), methylprednisone (1), betamethasone (1), beclomethasone (1) Thyroid hormone replacement therapy: ... oxazolidinones (6), cotrimoxazole (6), doxycycline (6), levofloxacin (6) Anti-tuberculous drugs: Use with caution:bedaquiline (1) (concomitant administration should be avoided. If the benefit ..., More about Prednisone. Ratings & Reviews. Doxycycline has an average rating of 6.4 out of 10 from a total of 1629 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 26% reported a negative effect. Prednisone has an average rating of 7.6 out of 10 from a total of 851 ratings on Drugs.com. 70% of reviewers reported a ..., Methods. This was a randomized, blinded, placebo-controlled trial in patients with mild-to-moderate COVID-19 symptoms randomly assigned to treatment (n = 200) and placebo (n = 200) groups. The primary outcome was duration from treatment to clinical recovery. Secondary outcomes were disease progression and persistent COVID-19 positivity by RT-PCR., Antihistamines. Antihistamines can be safely taken with a Prescription as they don’t really interact with one another. Common antihistamines include Benadryl, Claritin, Allegra, Zyrtec etc. Nasal decongestants. Nasal decongestants like Pseudoephedrine and Phenylephrine can be used along with Prednisone. However, the doses should be adjusted ..., For the treatment of pimples from rosacea: Adults—40 milligrams (mg) or one capsule once a day, in the morning. Children—Use and dose must be determined by your doctor. For oral dosage form (Doryx® delayed-release capsules, Doryx® delayed-release tablets): For anthrax after possible exposure: Delayed-release capsules:, Yes, Xanax and prednisone can be taken together. There is only a minor interaction between the two. Minor interactions do not usually cause harm OR require a change in therapy. Your health care provider will determine if adjustments to your medication are needed. Certain corticosteroids may decrease the plasma concentration of some benzodiazepines., CE is closely related to RIF occurrence, and the combined oral administration of prednisone acetate and doxycycline can be a treatment option for patients with RIF with CE and improves reproductive outcomes, although it does not improve the CE cure rate compared with doxycycline treatment alone., We chose doxycycline because oxytetracycline requires participants to swallow eight large tablets daily and doxycycline has fewer adverse effects. 20 We chose a dose of 0·5 mg/kg per day of prednisolone because a previous systematic review suggested higher doses were associated with unacceptable serious adverse effects 16 …, Shop Collection. Amoxicillin, a member of the penicillin family, is a broad-spectrum antibiotic that exhibits potent activity against a wide range of bacteria. It belongs to the beta-lactam class of antibiotics and works by inhibiting the synthesis of bacterial cell walls, leading to their destruction. View Catalogue., prednisone, clindamycin, dexamethasone, sulfamethoxazole / trimethoprim, Bactrim, rifampin, Decadron, Deltasone, Cleocin. Images. Dapsone 100 mg (N 136) View all images. Drugs.com Mobile Apps. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and ..., Cautions with other medicines. There are some medicines that do not mix well with doxycycline. Before taking it, tell your doctor if you're already taking any of these medicines: indigestion remedies ( antacids) stomach ulcer medicines that contain bismuth such as Pepto-Bismol. other antibiotics, such as rifampicin., The short answer is yes, you can take prednisone and ibuprofen together. However, there are a few important factors to consider. It's crucial to consult with your healthcare provider before combining these medications, as they may interact with each other or exacerbate certain conditions. Prednisone is a corticosteroid that helps reduce ..., Common side effects. These common side effects of doxycycline happen in around 1 in 10 people. There are things you can do to help cope with them: Headaches. Feeling sick (nausea) Being sick (vomiting) Skin being sensitive to sunlight. Speak to a doctor or pharmacist if the advice on how to cope does not help and the side effect is still ..., Some patients do use both. However, speak to your doctor about the proper protocol for using both together. You may need additional medications and monitoring for acid production, and a few other considerations., Doxycycline And Prednisone Taken Together buy Cheap, Best Prices Online, Free Prescription, No RX for sale, Now allow you to easily and discreetly purchase online, available as a lower-cost generic. Learn about products for healthcare., It's safe to take most Tylenol products and prednisone together, as long as you're mindful of the dosage. If you do experience these side effects while using Tylenol and prednisone, call your ..., Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated 1 Apr 2024), Cerner Multum™ (updated 21 Apr 2024), ASHP (updated 10 Apr 2024) and others., It's important to take doxycycline while you're in an upright position. You can be sitting, standing or walking. This will stop the medicine irritating your food pipe or stomach. Avoid lying down for at least 30 minutes after taking doxycycline. If you take it twice a day, this could be first thing in the morning, and in the evening - before ..., Doxycycline is an antibiotic commonly used to treat the bacterial infection responsible for pneumonia. Prednisone is a strong steroid used to reduce the inflammation in the airways to help with the COPD flare up. They can be used together without problem in most cases., Xarelto disease interactions. There are 6 disease interactions with Xarelto (rivaroxaban) which include: bleeding. valvular heart disease. antiphospholipid syndrome. hepatic impairment. renal disease. unstable blood pressure., Summary: Drug interactions are reported among people who take Dayquil and Doxycycline. Common interactions among females include anxiety and cough. Common interactions among males include alcohol intolerance and amnesia. The phase IV clinical study analyzes what interactions people have when they take Dayquil and Doxycycline together., The dose is usually 2.2 mg per kg of body weight per day, 2 times a day for 60 days. For oral dosage form (delayed-release capsules): For the treatment of pimples from rosacea: Adults—40 milligrams (mg) or one capsule once a day, in the morning. Children—Use and dose must be determined by your doctor., Xarelto disease interactions. There are 6 disease interactions with Xarelto (rivaroxaban) which include: bleeding. valvular heart disease. antiphospholipid syndrome. hepatic impairment. renal disease. unstable blood pressure., More about Prednisone. Ratings & Reviews. Doxycycline has an average rating of 6.4 out of 10 from a total of 1629 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 26% reported a negative effect. Prednisone has an average rating of 7.6 out of 10 from a total of 851 ratings on Drugs.com. 70% of reviewers reported a ..., Mucinex and Prednisone may have similar side effects, such as dizziness, nausea, and stomach upset. Taking them together may increase the risk of experiencing these side effects. Additionally, Prednisone can weaken the immune system, which might make it harder for your body to fight off infections. This is something to consider, especially if ..., A total of 222 drugs are known to interact with omeprazole . Omeprazole is in the drug class proton pump inhibitors . Omeprazole is used to treat the following conditions: Barrett's Esophagus. Duodenal Ulcer. Erosive Esophagitis. Gastritis/Duodenitis (off-label) GERD. Helicobacter Pylori Infection., The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Prednisone together. It is created by eHealthMe based on data from the FDA, and is updated regularly. Do you take Doxycycline and Prednisone? Personalize this study to your gender and age., Doxycycline can also be used to prevent malaria and treat infections caused by mites, ticks, or lice. Doxycycline hyclate and doxycycline monohydrate are two different salt forms of doxycycline available; one difference between the two is that doxycycline hyclate is soluble in water, while doxycycline monohydrate is very slightly …, no idea. PREDNISONE are 10MG tablets 5 day 1, 5 day 2, 4 day 3, 4 day 4, 3 day 5, 3 day 6, 2 day 7, 2 day 8, 1 day 9, 1 day 10 friday will be day 5. DOXY is 100MG capsules, 2/day for 30 days. I read that this should be more, like up to 600mg day? TICKER, I will go by those guidelines, thank you., Mercaptopurine Interactions. There are 280 drugs known to interact with mercaptopurine, along with 5 disease interactions, and 1 alcohol/food interaction.Of the total drug interactions, 56 are major, 208 are moderate, and 16 are minor., Always consult your healthcare provider before starting or stopping any medication. Major. Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderate. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances., Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated 1 Apr 2024), Cerner Multum™ (updated 21 Apr 2024), ASHP (updated 10 Apr 2024) and others.