Report on carcinogens

The Report on Carcinogens (RoC) is a congressionally mandated, science-based, public health document that NTP prepares. Substances listed in the RoC were evaluated for cancer hazards using a formal process and established listing criteria. Completed cancer hazard evaluations listed on this page include evaluations of …

Report on carcinogens. Dec 21, 2021 · In a study of benzene levels in homes, the median level was 2.2 ppb (7 μg/m 3) in 185 homes without smokers and 3.3 ppb (10.5 μg/m 3) in 343 homes with one or more smokers. Amounts of benzene measured per cigarette ranged from 5.9 to 75 μg in mainstream smoke and from 345 to 653 μg in sidestream smoke.

The report should contain the following elements: 1. A list of all substances (1) which either are known to be human carcinogens or may reasonably be anticipated to be human carcinogens and (2) to which a significant number of persons residing in the United States are exposed. 2. Information concerning the nature of such exposure

The report identifies agents, substances, mixtures, or exposures in two categories: known to be a human carcinogen and reasonably anticipated to be a human carcinogen. A listing in the Report on Carcinogens does not by itself mean that a substance will cause cancer. The Office of the Report on Carcinogens — headed by Ruth M. Lunn, Dr.P.H — coordinates one of the NTP's hazard evaluation activities. The Office of the RoC's scientific staff, with assistance from the RoC support contract staff, prepares the Report on Carcinogens, a congressionally mandated report that identifies substances or exposure circumstances that may pose a hazard to human health ...NTP Report on Carcinogens 1998 Background Document for Isoprene. levels of several other low-molecular-weight NMHCs, which are at a maximum in the winter and decline in the summer. Arnts and Meeks (1980) estimated that less than 10% ofNMHCs in rural and remote areas is biogenic.“We’ve seen studies published that measured the health and economic benefits of regulatory actions,” said Suril Mehta, Dr.P.H., an epidemiologist in the Report on Carcinogens (RoC) Group and a co-author on the new commentary. “But we could not find any papers that looked at the impact of a cancer hazard evaluation.” Sixth Annual Report on Carcinogens, one epidemiological study of BHA has been identi-fied. A population-based nested case-control study of stomach cancer in men and women within the Netherlands Cohort Study of dietary intake found no increase in risk at typical levels of dietary intake of BHA (Botterweck. et al. 2000). Properties 3 Feb 2021 ... Public Health Service, National Toxicology. Program. Report on Carcinogens, Fourteenth Edition. 2016. Accessed at http://ntp.niehs.nih.gov/ ...NTP Report on Carcinogens 1997 Background Document for Saccharin Proposed Report on Carcinogens Delisting for Saccharin. 1 . Saccharin is currently listed in the Report on Carcinogens, 8th Edition as reasonably anticipated to be a human carcinogen. The basis for this listing was sufficient evidence of carcinogeniC-ity in experimental animals.o-Toluidine was first listed in the Third Annual Report on Carcinogens as reasonably anticipated to be a human carcinogen based on sufficient evidence from studies in experimental animals. Since that time, additional cancer studies in humans have been published, and the listing was changed to known to be a human carcinogen in the Thirteenth ...

Jan 30, 2019 · arately) as known to be a human carcinogen, follow this introduction. Tobacco Smoking CAS No.: none assigned Known to be a human carcinogen First listed in the Ninth Report on Carcinogens (2000) Carcinogenicity Tobacco smoking is known to be a human carcinogen based on suffi-cient evidence of carcinogenicity from studies in humans. Cancer ... May 7, 2024 · Abstract. U.S. Department of Health and Human Services released the 14th Report on Carcinogens November 2016. The RoC is a congressionally mandated, science-based, public health document that NTP prepares for the HHS Secretary. This cumulative report currently includes 248 listings of agents, substances, mixtures, and exposure circumstances ... Dec 21, 2021 · The agents, substances, mixtures, or exposure circumstances contained in this appendix were previously listed in the Report on Carcinogens (RoC) as either known or reasonably anticipated to be human carcinogens. For substances removed from the RoC prior to the 1996 establishment of a formal review procedure for delisting substances from the RoC, Table B-1 below shows the reason for delisting ... Historical Highlights of the Report on Carcinogens Criteria Listing Review Process. Since the RoC's inception in 1978, NTP has used scientifically rigorous processes and established listing criteria to evaluate substances for the RoC. The Board of Scientific Counselors (BSC) and the public have provided input leading to several evolutions of ...15th Report on Carcinogens [Internet]. Reserpine. Reasonably anticipated to be a human carcinogen. First listed in the Second Annual Report on Carcinogens (1981) Also known as methyl 18β-hydroxy-11,17α-dimethoxy-3β,20α-yohimban-16β-carboxylate 3,4,5-trimethoxybenzoate (ester)Dec 21, 2021 · Appendix A. Cancer Hazards Not Included in the NTP Report on Carcinogens; Appendix B. Substances Delisted from the Report on Carcinogens; Appendix C. Substances Reviewed but Not Recommended for Listing in the Report on Carcinogens; Appendix D. 15th RoC and Monographs - Collaborators and Contributors Properties. Elemental chromium is a transition-group metal belonging to group VIB of the periodic table and has oxidation states ranging from −2 to +6, of which the divalent (+2, II), trivalent (+3, III), and hexavalent (+6, VI) forms are the most important. Elemental chromium does not occur naturally in the environment.

According to About.com, petroleum jelly, which is found in Vaseline, contains polycyclic aromatic hydrocarbons from unrefined petrolatum that are considered to be carcinogenic. Whi...In its Report on Carcinogens, the National Toxicology Program of the US Department of Health and Human Services lists consumption of alcoholic beverages as a known human carcinogen. The evidence indicates that the more alcohol a person drinks—particularly the more alcohol a person drinks regularly over time—the higher his or her risk of ...The Report on Carcinogens is a congressionally mandated, science-based public health document that NTP prepares for the HHS Secretary. This cumulative report now includes 256 listings of substances — chemical, physical, and biological agents; mixtures; and exposure circumstances — that are known or reasonably anticipated to cause cancer in ...Dec 21, 2021 · Nickel compounds as a class were first listed as known to be human carcinogens in the Tenth Report on Carcinogens (2002); this listing supersedes the listing of “certain nickel compounds” and applies to all members of the class. Metallic nickel was reevaluated in 2000 and remains listed as reasonably anticipated to be a human carcinogen.

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Since 1,4-dioxane was listed in the Second Annual Report on Carcinogens, additional studies in rodents have been identified. 1,4-Dioxane administered in the drinking water increased the combined incidence of benign and malignant liver tumors (hepatocellular adenoma and carcinoma) in rats and mice of both sexes.Nickel and certain nickel compounds have been listed in the Report on Carcinogens (RoC) since 1980 as . reasonably anticipated to be human carcinogens. In February 1998, the National Toxicology Program announced its intention to review nickel and nickel compounds for possible upgrading and/or listing for the first time in the RoC. The ...Progesterone is a steroid hormone that is an odorless white crystalline powder at room temperature. It is practically insoluble in water, sparingly soluble in vegetable oils, and soluble in acetone, alcohol, dioxane, and concentrated sulfuric acid. It is sensitive to light, but stable in air ( IARC 1979 ).Abstract. The Report on Carcinogens (RoC) is an informational scienti.c and public health document that identifies and discusses agents, substances, mixtures, or exposure circumstances (hereinafter referred to as substances) that may pose a hazard to human health by virtue of their carcinogenicity. For each listed substance, the RoC contains a ...Since 1,4-dioxane was listed in the Second Annual Report on Carcinogens, additional studies in rodents have been identified. 1,4-Dioxane administered in the drinking water increased the combined incidence of benign and malignant liver tumors (hepatocellular adenoma and carcinoma) in rats and mice of both sexes.

Verdict: TRUE. The colour of plastic does not inherently determine its chemical content; it is the composition and manufacturing process that dictate whether harmful substances are present. The ...The Report on Carcinogens (RoC) is an informational scientific and public health document that identifies and discusses agents, substances, mixtures, or exposure circumstances that may pose a hazard to human health by virtue of their carcinogenicity. It serves as a meaningful and useful compilation of data on (1) the carcinogenicity (ability …The Report on Carcinogens classifies substances as “Known to be human carcinogens” or “Reasonably anticipated to be a human carcinogen.” IARC uses a more complex classification scheme which includes substances that have been reviewed but are found not classifiable as possibly carcinogenic to humans: Group1, carcinogenic to humans; …The NTP cancer hazard evaluation was the basis for changing the listing status of TCE from reasonably anticipated to known to be a human carcinogen in the 14th edition of the Report on Carcinogens based on sufficient evidence …listed in the First Annual Report on Carcinogens as reasonably antic-ipated to be human carcinogens based on sufficient evidence of carci-nogenicity from studies in experimental animals and limited evidence of carcinogenicity from studies in humans; however, the listing was revised to known to be human carcinogens in the Sixth Annual Re-Jan 30, 2019 · arately) as known to be a human carcinogen, follow this introduction. Tobacco Smoking CAS No.: none assigned Known to be a human carcinogen First listed in the Ninth Report on Carcinogens (2000) Carcinogenicity Tobacco smoking is known to be a human carcinogen based on suffi-cient evidence of carcinogenicity from studies in humans. Cancer ... May 7, 2024 · Abstract. U.S. Department of Health and Human Services released the 14th Report on Carcinogens November 2016. The RoC is a congressionally mandated, science-based, public health document that NTP prepares for the HHS Secretary. This cumulative report currently includes 248 listings of agents, substances, mixtures, and exposure circumstances ... Certain manufacturing processes, occupations, and other exposure circumstances have been classified as carcinogens by authoritative sources, including the International Agency for Research on Cancer (IARC), the World Cancer Research Fund (WCRF), and the National Toxicology Program (NTP). These cancer hazards are not included in the Report on Carcinogens (RoC) either because of uncertainty as ...the Ninth Report on Carcinogens in 2000, the International Agency for Research on Cancer has reevaluated the evidence for the carcinoge-nicity of alcoholic beverage consumption (Baan et al. 2007, Secretan et al. 2009) and concluded that there was sufficient evidence of carci-nogenicity in humans. The 2007 and 2009 reviews concluded that al-Nitrobenzene is structurally related to other aromatic nitro and amino compounds, including several nitroarenes listed in the Report on Carcinogens as reasonably anticipated to be human carcinogens and classified by the International Agency for Research on Cancer as possibly carcinogenic to humans .Aristolochic acids are known to be human carcinogens based on sufficient evidence of carcinogenicity from studies in humans and supporting data on mechanisms of carcinogenesis. Evidence of carcinogenicity from studies in experimental animals supports the findings in humans.Nitromethane is a nitroalkane compound that is a colorless oily liquid with a fruity odor at room temperature. It is soluble in water, alcohol, ether, acetone, and dimethylformamide. Nitromethane is sensitive to shock and is unstable when heated. It also forms an explosive sodium salt that bursts into flame on contact with water ( Akron 2009 ).

Appendix A. Cancer Hazards Not Included in the NTP Report on Carcinogens; Appendix B. Substances Delisted from the Report on Carcinogens; Appendix C. Substances Reviewed but Not Recommended for Listing in the Report on Carcinogens; Appendix D. 15th RoC and Monographs - Collaborators and Contributors

Report on Carcinogens, Fifteenth Edition For definitions of technical terms, see theGlossary. The U.S. Food and Drug Administration has regulated the use of acrylamide and polyacrylamide in foods (IARC 1994). Acrylamide polymers containing less than 0.2% monomer may be used in food-packaging adhesives, paper, and paperboard; to wash or peel fruitsHeterocyclic amines (HCAs) are formed during the cooking of meat, by condensation of creatinine with amino acids. Four individual HCAs are listed in the Report on Carcinogens as reasonably anticipated to be a human carcinogen (in separate listings): 2-Amino-3,4-dimethylimidazo [4,5- f ]quinoline (MeIQ) was first listed in the Eleventh …When it comes to making informed decisions about the products and services you buy, it pays to do your research. Consumer Reports is one of the more trusted sources for unbiased pr...3,3′-Dichlorobenzidine and 3,3′-dichlorobenzidine dihydrochloride are reasonably anticipated to be human carcinogens based on sufficient evidence of carcinogenicity from studies in experimental animals. The names 3,3′-dichlorobenzidine and 3,3′-dichlorobenzidine dihydrochloride are used interchangeably in the published …listed in the First Annual Report on Carcinogens as reasonably antic-ipated to be human carcinogens based on sufficient evidence of carci-nogenicity from studies in experimental animals and limited evidence of carcinogenicity from studies in humans; however, the listing was revised to known to be human carcinogens in the Sixth Annual Re-Polypropylene is safe and is not considered a health hazard. It is a thermosetting plastic that does not degrade quickly. It does not contain carcinogens and other compounds that c...1-Bromopropane is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals. 1-Bromopropane, either directly or via reactive metabolites, causes molecular alterations that typically are associated with carcinogenesis, including genotoxicity, oxidative stress, and …The Report on Carcinogens identifies many different environmental factors, collectively called substances, including chemicals; infectious agents, such as viruses; physical agents, such as... Since 1,4-dioxane was listed in the Second Annual Report on Carcinogens, additional studies in rodents have been identified. 1,4-Dioxane administered in the drinking water increased the com-bined incidence of benign and malignant liver tumors (hepatocellu-lar adenoma and carcinoma) in rats and mice of both sexes. Since 1,4-dioxane was listed in the Second Annual Report on Carcinogens, additional studies in rodents have been identified. 1,4-Dioxane administered in the drinking water increased the combined incidence of benign and malignant liver tumors (hepatocellular adenoma and carcinoma) in rats and mice of both sexes.

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nual Report on Carcinogens as reasonably anticipated to be a human carcinogen based on sufficient evidence from studies in experimen-tal animals. “Respirable” fibers are those that can penetrate into the alveolar region of the lung upon inhalation (EPA 2001) (see Prop-erties for a more detailed description). Since that time, additionalIn 2013, it was estimated that pesticide contamination resulted in the death of 20 million birds annually; since dead birds are rarely recovered, the actual figure is probably much higher.ArticlePDF Available. Final Report on Carcinogens Background Document for Formaldehyde. January 2010. Authors: Luoping Zhang. University of California, Berkeley. Ruth Mae Lunn.The Report on Carcinogens (RoC) is a Congressionally mandated, science-based public health document that identifies and discusses agents, substances, mixtures, or exposure circumstances (collectively referred to as “substances”) that pose a cancer hazard for persons in the United States. Substances are listed in the report as either known or …The Report on Carcinogens review groups considered the data underlying the nomination to remove ethyl acrylate from the Report on Carcinogens, where it has been listed as reasonably anticipated to be a human carcinogen since 1989. The basis for this listing was a gavage study that resulted in dose-related benign and malignant …Many nitrosamines are potent carcinogens, with more than 30 listed under California’s Proposition 65. Recently, nitrosamine contamination of commonly used drugs for treatment of hypertension, heartburn, and type 2 diabetes has prompted numerous Food and Drug Administration (FDA) recalls in the US. These contaminants include the …Dec 21, 2021 · Nickel compounds as a class were first listed as known to be human carcinogens in the Tenth Report on Carcinogens (2002); this listing supersedes the listing of “certain nickel compounds” and applies to all members of the class. Metallic nickel was reevaluated in 2000 and remains listed as reasonably anticipated to be a human carcinogen. Since 4-dimethylaminoazobenzene was listed in the Second Annual Report on Carcinogens, additional studies in rodents have been identified. Dietary administration of 4-dimethylaminoazobenzene to male mice for 14 months resulted in development of benign and malignant liver tumors (adenoma after 104 days and carcinoma after 10 … ….

The Report on Carcinogens (RoC) is a scientific public health document on cancer hazards to which people in the U.S. may be exposed. Published biennially, each edition of the report is cumulative and consists of substances newly reviewed in addition to those listed in previous editions. Report on Carcinogens, Fifteenth Edition For definitions of technical terms, see theGlossary. chemical composition of a field sample seldom matches the idealized formula. Amphibole fibers do not divide into fibrils as small in di-ameter or as symmetrical as chrysotile fibers, and they do not have a hollow central core. Certain manufacturing processes, occupations, and other exposure circumstances have been classified as carcinogens by authoritative sources, including the International Agency for Research on Cancer (IARC), the World Cancer Research Fund (WCRF), and the National Toxicology Program (NTP). These cancer hazards are not included in the Report on Carcinogens (RoC) either because of uncertainty as ...The Report on Carcinogens (RoC) is an informational scientific and public health document that identifies and discusses agents, substances, mixtures, or exposure circumstances that may pose a hazard to human health by virtue of their carcinogenicity.Progesterone is a steroid hormone that is an odorless white crystalline powder at room temperature. It is practically insoluble in water, sparingly soluble in vegetable oils, and soluble in acetone, alcohol, dioxane, and concentrated sulfuric acid. It is sensitive to light, but stable in air ( IARC 1979 ).Ethyl methanesulfonate is the ethyl ester of methanesulfonic acid and exists as a colorless liquid at room temperature ( IARC 1974 ). It is soluble in water and stable under normal temperatures and pressures ( Akron 2009 ). Physical and chemical properties of ethyl methanesulfonate are listed in Table 1. Table 1.The Report on Carcinogens includes two separate listings (i.e., profiles) for cobalt-related exposures: Cobalt and Cobalt Compounds That Release Cobalt Ions In Vivo and Cobalt-Tungsten Carbide: Powders and Hard Metals. Cobalt and cobalt compounds as a class are listed for the first time in the Fourteenth Report on Carcinogens, and this …nual Report on Carcinogens as reasonably anticipated to be a human carcinogen based on sufficient evidence from studies in experimen-tal animals. “Respirable” fibers are those that can penetrate into the alveolar region of the lung upon inhalation (EPA 2001) (see Prop-erties for a more detailed description). Since that time, additionalN-Nitrosamines are a class of chemical compounds with the general structure shown in the figure. The essential feature of N-nitroso compounds is the N–N=O structure; the R1 and R2 groups attached to the amine nitrogen may range from a simple hydrogen (H) atom to more complex chemical substituents (including ring structures that incorporate the nitrogen atom), as shown in the structures of ... Report on carcinogens, Cobalt is a transition element and a component of more than 70 naturally occurring minerals. It is often combined with other metals to make metal alloys or cemented carbides for a variety of medical or commercial applications; some cobalt compounds are used as pigments or in electronic devices. People can be exposed to cobalt or its compounds in …, Thiotepa is known to be a human carcinogen based on sufficient evidence from studies in humans. Thiotepa was first listed in the Second Annual Report on Carcinogens in 1981 as reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals and insufficient evidence of carcinogenicity from studies in humans., Office of the Report on Carcinogens. The United States federgovernment's NIEHS National Toxicology Program's Office of the Report on Carcinogens is responsible for publishing a Report On Carcinogens, first issued in 1980. The latest edition is the 15th Report, issued in 2021. , FULL STORY. December 11, 2002 -- The federal government today published its biennial Report on Carcinogens, adding steroidal estrogens used in estrogen replacement therapy and oral contraceptives ..., The Report on Carcinogens (RoC) is prepared in response to Section 301 of the Public Health Service Act as amended. The RoC contains a list of identified substances (i) that either are known to be human carcinogens or are reasonably be anticipated to be human carcinogens and (ii) to which a significant number of persons residing in the United, Epidemiological studies and case reports of humans exposed to arsenic or arsenic compounds for medical treatment, in drinking water, or occupationally have demonstrated that exposure to arsenic and inorganic arsenic compounds increases the risk of cancer. Cancer tissue sites include the skin, lung, digestive tract, liver, urinary bladder ..., USA.gov. Certain glass wool fibers (inhalable) are reasonably anticipated to be human carcinogens based on (1) sufficient evidence of carcinogenicity from studies in experimental animals of inhalable glass wool fibers as a class (defined below) and (2) evidence from studies of fiber properties which indicates that only certain fibers within ..., chloromethane— are listed in the Report on Carcinogens as reason-ably anticipated to be a human carcinogen. The U.S. Environmental Protection Agency (EPA) regulates the mixture of five haloacetic ac-ids mentioned above, two of which (dichloroacetic acid and dibro-moacetic acid) are included in this listing., Report on Carcinogens, Fifteenth Edition For definitions of technical terms, see theGlossary. chemical composition of a field sample seldom matches the idealized formula. Amphibole fibers do not divide into fibrils as small in di-ameter or as symmetrical as chrysotile fibers, and they do not have a hollow central core., The report should contain the following elements: 1. A list of all substances (1) which either are known to be human carcinogens or may reasonably be anticipated to be human carcinogens and (2) to which a significant number of persons residing in the United States are exposed. 2. Information concerning the nature of such exposure, The NTP cancer hazard evaluation was the basis for changing the listing status of TCE from reasonably anticipated to known to be a human carcinogen in the 14th edition of the Report on Carcinogens based on sufficient evidence of carcinogenicity from studies in humans. , Report on Carcinogens (RoC) Concept: Cobalt Project Leader: Diane L. Spencer, MS, Office of the RoC, DNTP, NIEHS 1 Background and rationale 1.1 Background Cobalt metal (CAS No. 7440-48-4) is a naturally occurring shiny brittle silver-gray metallic element with ferromagnetic properties, which is used in a variety of industrial applications., The Report on Carcinogens (RoC) (previously known as the Annual Report on Carcinogens) is a Congressionally mandated listing of known human carcinogens and reasonably anticipated human carcinogens whose preparation is delegated to the National Toxicology Program by the Secretary, Department of Health and Human Services (DHHS)., Since technical grade 1,3-dichloropropene was listed in the Fifth Annual Report on Carcinogens, an ecological case-control study of pancreatic cancer mortality (from 1989 to 1996) and exposure to organochlorine pesticides was reported. The authors reported an increase in pancreatic cancer mortality among long-term residents in areas …, A Mississauga factory is using a known carcinogen. Residents had no idea. High levels of ethylene oxide were detected near a now-closed Scarborough plant owned by Sterigenics, which has agreed to pay over US$400 million to claimants alleging cancer in the U.S. The company has since moved to Mississauga. By Leah Borts-Kuperman and …, The Report on Carcinogens identifies many different environmental factors, collectively called substances, including chemicals; infectious agents, such as viruses; physical agents, such as X-rays and ultraviolet radiation; and exposure scenarios. A substance is listed as either known to be a human carcinogen or reasonably anticipated …, Thiotepa is known to be a human carcinogen based on sufficient evidence from studies in humans. Thiotepa was first listed in the Second Annual Report on Carcinogens in 1981 as reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals and insufficient evidence of carcinogenicity from studies in humans., Abstract. The National Toxicology Program conducted a cancer evaluation on cumene for possible listing in the Report on Carcinogens (RoC). The cancer evaluation is captured in the RoC monograph, which was peer reviewed in a public forum. The monograph consists of two components: (Part 1) the cancer evaluation, which reviews the relevant ..., 1-Bromopropane is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals. 1-Bromopropane, either directly or via reactive metabolites, causes molecular alterations that typically are associated with carcinogenesis, including genotoxicity, oxidative stress, and …, Report on Carcinogens, Fifteenth Edition For definitions of technical terms, see theGlossary. chemical composition of a field sample seldom matches the idealized formula. Amphibole fibers do not divide into fibrils as small in di-ameter or as symmetrical as chrysotile fibers, and they do not have a hollow central core., According to the National Cancer Institute, consuming food that has been cooked beyond a temperature of 248 degrees fahrenheit, which includes burned popcorn, may carry a health ri..., The Report on Carcinogens is a congressionally mandated, science-based public health document that the National Toxicology Program prepares for the Secretary of Health and Human Services. This cumulative report includes listings of substances—chemical, physical, and biological agents; mixtures; and exposure circumstances—that are known …, The Report on Carcinogens is a congressionally mandated, science-based, public health document that provides a cumulative list of substances that pose a cancer hazard for people in the United States. Su bstances are reviewed for the Report on Carcinogens to, Report on Carcinogens . The Report on Carcinogens (RoC) is a Congressionally mandated, science-based public health document that identifies and discusses . agents, substances, mixtures, or exposure circumstances (collectively referred to as “substances”) that pose a cancer hazard for persons in the United States. Substances are listed in ..., The Report on Carcinogens (RoC) (previously known as the Annual Report on Carcinogens) is a Congressionally mandated listing of known human carcinogens and reasonably anticipated human carcinogens whose preparation is delegated to the National Toxicology Program by the Secretary, Department of Health and Human Services (DHHS)., The data available from epidemiological studies are inadequate to evaluate the relationship between human cancer and exposure specifically to toxaphene. Since toxaphene was listed in the Second Annual Report on Carcinogens, additional epidemiological studies have been identified. Two case-control studies, one for non …, Since 1,2,3-trichloropropane was listed in the Eighth Report on Carcinogens, an additional study in experimental animals has been identified. Exposure to 1,2,3-trichloropropane in the aquarium water of guppies ( Poecilia reticulata) and medaka ( Oryzias latipes) caused liver tumors in males and females of both species and benign …, In 1981, The National Toxicology Program (NTP) first listed formaldehyde in the 2nd Report on Carcinogens as "reasonably anticipated to be a human carcinogen". In 2011, NTP upgraded the listing of formaldehyde to "known to be a human carcinogen"., Vinyl bromide (Note: For practical purposes, vinyl bromide should be considered to act similarly to the human carcinogen vinyl chloride.) Vinyl fluoride (Note: For practical purposes, vinyl fluoride should be considered to act similarly to the human carcinogen vinyl chloride.) National Toxicology Program 15th Report on Carcinogens , Since asbestos was listed in the First Annual Report on Carcinogens, the evidence for the carcinogenicity of asbestos has been reevaluated by the Institute of Medicine (IOM) of the National Academy of Sciences in 2006 and by IARC in 2009 (Straif et al. 2009). IARC concluded that exposure to all forms of asbestos (chrysotile, crocidolite ..., Formaldehyde is known to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in humans and supporting data on mechanisms of carcinogenesis. Formaldehyde was first listed in the Second Annual Report on Carcinogens in 1981 as reasonably anticipated to be a human carcinogen based on …, Radon is a naturally occurring, odorless, and colorless gas that can be found in homes and buildings. It is a known carcinogen and can be hazardous to your health if it accumulates..., o-Toluidine was first listed in the Third Annual Report on Carcinogens as reasonably anticipated to be a human carcinogen based on sufficient evidence from studies in experimental animals. Since that time, additional cancer studies in humans have been published, and the listing was changed to known to be a human carcinogen in the Thirteenth ...