Neosporin sulfa allergy

Be aware, there are a variety of different antibiotic eye ointments for adults, as well as children available. Some of the most commonly prescribed of these include: Bacitracin: A polypeptide, brand name Baciguent. Ciprofloxacin: A quinolone, brand name Ciloxan. Erythromycin: A macrolide, brand names Eyemycin, Ilotycin, and Roymicin.

2. Apply calamine lotion. If you are experiencing a rash or hives caused by an allergic reaction, calamine lotion may help soothe the itching and discomfort. [20] Calamine lotion contains a mixture of calamine, zinc oxide, and other ingredients. Calamine and zinc oxide are both known anti-itch topical medications.Options for treatment of mild to moderate nonpurulent infections include cefazolin, ceftriaxone, clindamycin, and penicillin [ 6 ]. Although there is a lack of data to support the optimal duration of antibiotic therapy, the guidelines recommend a treatment duration of 7-10 days [ 6 ].Neomycin allergy is diagnosed by performing patch tests and in some cases intradermal tests. A 20% neomycin in petrolatum is the recommended concentration used for patch testing. A positive reaction shows a delayed indurated papule appearing after 48–72 hours. The patch test may not always be positive. If the test is negative, an intradermal ...Antibiotics, especially sulfonamides, are among the most common causes of allergic reactions to drugs. 1,2 Reactions to sulfonamide antibiotics occur in approximately 3 percent of courses, 3,4 ...I am a RN, practiced for 40 years. During that time I never saw an allergic reaction to Neosporin - until Feb 2016. My cat scratched my leg and after cleaning it was using Neosporin cream - but it got worse, went to my doctor who didn't know what it was, and gave me a sulfa cream and tablets, since I'm allergic to penicillin.5. Goldenseal. Goldenseal is usually consumed in tea or capsules. Proponents may use goldenseal to help treat respiratory and digestive problems. While more research is necessary, some evidence ...Neosporin: Clinical 2 nd /3 rd degree burns : Polymyxin B: ... It is a good alternative to silver sulfadiazine (Silvadene) for burn patients with a sulfa allergy ...If you’re one of the millions of people who suffer from allergies, you know how important it is to keep your home clean and free from allergens. One of the best ways to do this is ...

The most common bacterial causes of skin and soft tissue infections (SSTI) are group A Streptococcus (GAS) and Staphylococcus aureus, the key bacterial agents of impetigo, cellulitis, abscesses, and wound infections [].Impetigo is driven by GAS in resource-poor settings []; however, in developed settings, impetigo, including bullous impetigo, is more likely to have S aureus present [].Our purpose is to present an evidence-based approach, directed primarily towards eye-care specialists, clarifying whether certain drugs should or should not be …However, if the patient has a history of a severe allergy (eg, Stevens-Johnson syndrome, toxic epidermal necrolysis), TMP-SMX should be avoided and desensitization should not be performed. (See "Treatment and prevention of Pneumocystis infection in patients with HIV", section on 'Desensitization for patients with a sulfa allergy' and ...2. Neosporin is a triple antibiotic ointment, made up of bactracin, neomycin and polymyxin B. Antibiotics work to kill bacteria on the skin, thereby preventing or curing a brewing infection. This allows Neosporin on dogs to effectively prevent infections in minor wounds, such as cuts or scrapes. Many types of Neosporin also contain a topical ...Safeguards Are in Place. Everyone who gets a COVID-19 vaccine may be monitored onsite for at least 15 minutes after vaccination. You had an immediate (within 4 hours) allergic reaction that was not severe from a previous dose of that type of COVID-19 vaccine. You've had a non-severe allergic reaction to an ingredient used in the COVID-19 vaccine.Common side effects of sulfonamides may include itching, skin rash, increased sensitivity to sunlight, diarrhea, dizziness, headache, loss of appetite, nausea or vomiting, and fatigue.

Jan 15, 2020 · Pros and cons. Alternatives. Summary. Neosporin is a brand of triple antibiotic ointment. Bacitracin is also an antibiotic ointment, but it only contains one type of antibiotic. While both types ... Neomycin-containing compounds are discouraged because of the risk of allergic reaction (approximately 10%). 18 The addition of topical steroids decreases the time to symptom resolution without ...Skin tests. With a skin test, the allergist or nurse administers a small amount of a suspect drug to your skin either with a tiny needle that scratches the skin, an injection or a patch. A positive reaction to a test often causes a red, itchy, raised bump. A positive result suggests you may have a drug allergy.Subtotal. $43.70. FR - TVA réduite de 5.5% (5.5%) $2.28. Tax. $2.28. Proceed to Checkout. The usual application timetable involves taking this drug from 2 to 4 times daily, depending on the type of condition you have and exactly how intense it is Bactrim (sulfamethoxazole and trimethoprim) is a combination drug made use of for the procedure of ...

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A 2022 study explains that neomycin — one of the ingredients in Neosporin — is one of the most common contact allergens in North America. If you are allergic to neomycin but can use bacitracin and polymyxin B, then opting for a bacitracin and polymyxin B ointment can be a potential alternative. One such ointment is called Polysporin.We have a variety of NEOSPORIN® antibiotic products that may meet your needs: If allergic to Neomycin Sulfate, we recommend using our Neomycin-free products: SIMPLY NEOSPORIN™ or POLYSPORIN®, which contain double antibiotic drugs, Bacitracin Zinc and Polymyxin B Sulfate.The most common symptoms of beta-lactam allergy in patients with CF are pruritus and rash. 80 Koch et al 86 studied 121 patients with CF and found that 4.5% of the courses were associated with adverse reactions. However, most of these reactions were nonimmediate, such as maculopapular rashes and drug fever.Dog skin allergies can be a frustrating and uncomfortable condition for both pets and their owners. While some triggers, such as fleas or certain foods, are well-known, there are l...Pesticides or weed killers. Rubber gloves. Shampoos. Allergic contact dermatitis: This form of the condition occurs when your skin comes in contact with a substance that causes you to have an allergic reaction. Common allergens include: Adhesives, including those used for false eyelashes or toupees. Antibiotics, such as neomycin rubbed on the ...For otic dosage form (ear drops): For ear canal infection: Adults—4 drops into the affected ear 3 or 4 times a day. Children—3 drops into the ear 3 or 4 times a day. For mastoid cavity infection: Adults—4 to 10 drops in the ear every 6 to 8 hours. Children—4 or 5 drops in the ear every 6 to 8 hours.

INTRODUCTION. Antibiotics are one of the most common causes of drug allergy in most epidemiological studies, both among adults and children. 1-6 Among the various classes of antibiotics, beta-lactam antibiotics (penicillins and cephalosporins), cotrimoxazole and quinolones are some of the most common causes of antibiotic allergy. Antibiotic allergy may occur in the form of immediate or non ...Contact dermatitis to Neosporin is quite common and typically due to Neomycin which a very common cause of contact allergy. There should be no reason to "test" for sulfa allergy in this patient. I hope this is helpful. Best regards, Daniel J. Jackson, MD, FAAAAI. AAAAI's Ask the Expert talks about Neosporin contact dermatitis.Food allergy is common, affecting up to 8% of children and 10% of adults in the United States.1,2 Hospital admission data for food-induced anaphylaxis have shown a clear increasing trend in the Uni...INTRODUCTION. Methicillin resistance in Staphylococcus aureus (MRSA) is defined by the Clinical Laboratory Standards Institute (CLSI) as an oxacillin minimum inhibitory concentration (MIC) ≥4 mcg/mL [].According to the European Committee on Antimicrobial Susceptibility Testing (EUCAST), S. aureus with oxacillin MIC values >2 mg/L are mostly methicillin resistant [].Superficial ocular infections: Ophthalmic ½-inch ribbon in conjunctival sac q3-4h. Skin abrasions, superficial skin infections: Topical Apply to affected area 1-5 times a day. Surgical treatment and prophylaxis: Irrigation 50,000-150,000 units, as needed. Contraindications: None known.Causes. Treatment. Prevention. Takeaway. Like other drug allergies, a sulfa allergy may be accompanied with symptoms like hives, itchy skin, or swelling in the mouth or throat. It differs from a...allergic reaction to a sulfonamide antibiotic had a higher occurrence of allergic reactions than did patients with no history of hypersensitivity to sulfonamide antibiotics (9.9% versus 1.6%, adjusted odds ratio 2.8; 95% confidence interval, 2.1 to 3.7). However, patients with a prior sulfa allergy were even more likely to have an allergicAllergic contact dermatitis (ACD) caused by topical medicaments is a common and underrecognized entity in the family practice setting. The differential diagnosis of ACD might be overlooked for a number of reasons, including a lack of awareness of the characteristic features of ACD, anchoring bias toward the original concern for which a medicament was …Sulfa allergy is an adverse drug reaction, such as a rash, to sulfonamides, a class of drugs that includes antibiotics and other drugs. Allergies to sulfa drugs are common. Whether caused by a true allergy or drug intolerance, sulfa reactions happen at a rate similar to other types of antibiotics, including penicillin.Neomycin sulphate is an antibiotic commonly used in many prescription andover-the-counter antibacterial topical creams, powders and ointments, eye drops, and vaginal suppositories. It is also commonly found in dental and veterinary care products. Cross-reactivity may occur to other related aminoglycoside antibiotics, such as kanamycin ...

BACTROBAN ointment contains mupirocin (2% w/w) as the active ingredient. Mupirocin belongs to a group of medicines called antibiotics. Antibiotics work by killing bacteria which can cause ...

I'm allergic to Murpirocin, neosporin, bacitracin, clindamycin, metronidazole all topicals and had a syncope from a tetracycline type drug. ... (HCTZ), and the doctor said it was because she was allergic to sulfa. My sister had not put her sulfa allergy on her medical history form at the cardiologist's office, because the sulfa reaction had ...SPL UNCLASSIFIED SECTION. Drug Facts. ACTIVE INGREDIENT. Active ingredients (in each gram) Bacitracin Zinc (400 units) Neomycin Sulfate (3.5 mg) Polymyxin B sulfate (5,000 units) Purpose - First aid antibiotic. Use. first aid to help prevent infection in minor: cuts scrapes burns. Warnings.Neomycin and polymyxin B belong to the class of medicines known as antibiotics. They work by killing the bacteria or preventing their growth. Dexamethasone is a steroid medicine that is used to relieve the redness, itching, …There are two main side effects that may happen from using products like Neosporin. First, antibacterial ointments can dry and irritate your skin. Some people have allergic reactions to them. If you're sensitive to these ointments, using them can cause contact dermatitis, a painful, itchy rash.A 40-year-old man began oral treatment with ketoconazole at a dosage of 400 mg per day for prophylaxis of candidiasis. Forty minutes after administration of the first dose, he developed angioedema of the face in addition to generalized urticaria. The symptoms were quickly reduced by administration of parenteral steroids and anti-histaminics.Silver sulfadiazine cream is used to prevent and treat wound infections in patients with second- and third-degree burns. Patients with severe burns or burns over a large area of the body must be treated in a hospital. Silver sulfadiazine is an antibiotic. It works by killing the bacteria or preventing its growth.People with a sulfa allergy should avoid sulfonamide antibiotics, such as Septra and Bactrim, and some nonantibiotic drugs that contain sulfa. Learn about the types of drugs that may cause allergic reactions and how to weigh the risks and benefits of taking them.Neosporin + Pain Relief Max St side effects. Serious Side Effects. Yellowing of your skin or the whites of your eyes. Unusual bleeding, bruising, or weakness. Unexplained fever, chills, cough, sore throat, and body aches. Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest ...

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CORTISPORIN Otic Solution (neomycin and polymyxin B sulfates and hydrocortisone otic solution, USP) is a sterile antibacterial and anti-inflammatory solution for otic use. Each mL contains: neomycin sulfate equivalent to 3.5 mg neomycin base, polymyxin B sulfate equivalent to 10,000 polymyxin B units, and hydrocortisone 10 mg (1%).Polysporin side effects. Signs of wound or skin infection: increasing pain, redness, swelling, or drainage of fluid or pus that is cloudy, brown, green, or foul-smelling. New or worsening skin rash. New or worsening redness, burning, itching, or swelling in the area where the medicine is applied. Unexplained fever.Treatment is with Trimethoprim-Sulfamethoxazole (TMP-SMX) although other lines of therapy exist for those with allergies. This case illustrates the challenge of treating Pneumocystis pneumonia in patients with a severe allergy to sulfonamides. CASE PRESENTATION: 59-year-old Caucasian male presented with lightheadedness and …The following interventions may be used to treat the symptoms of an allergic reaction to penicillin: Withdrawal of the drug. If your doctor determines that you have a penicillin allergy — or likely allergy — discontinuing the drug is the first step in treatment. Antihistamines. Your doctor may prescribe an antihistamine or recommend an over ...can you take sulfa drugs?? I know some doctors recommend polysporin vs the neosporin. Here is something I copied from a website-"Neosporin contains Neomycin sulfate-3.5mg, Bacitracin-400 units and Polymyxin B 5000 units. Of course it does contain cocoa butter, olive oil may prevent the formation of scars. A 1/2 oz tube costs $5.For otic dosage form (ear drops): For ear canal infection: Adults—4 drops into the affected ear 3 or 4 times a day. Children—3 drops into the ear 3 or 4 times a day. For mastoid cavity infection: Adults—4 to 10 drops in the ear every 6 to 8 hours. Children—4 or 5 drops in the ear every 6 to 8 hours.NEOSPORIN ® is the number-one doctor recommended brand of topical antibiotic in the US. As with other topical antibiotics, it's typically used to treat skin infections and protect wounds from potential infection 1,2. NEOSPORIN ® products treat minor wounds such as scrapes, cuts and light burns. Products are also available to help minimize the ...Lexi-comp (online.lexi.com) has a drug allergy and idiosyncratic reactions database that is searchable by drug class. For example, for levofloxacin allergy search "fluoroquinolone allergy." There is also a review of penicillin cross reactivity under "penicillin allergy." Figure: Penicillin Core Structure Selected References: 1. ….

A leukotriene inhibitor is a prescription medication that blocks symptom-causing chemicals called leukotrienes. This oral medication relieves allergy signs and symptoms including nasal congestion, runny nose and sneezing. Only one type of this drug, montelukast (Singulair), is approved for treating hay fever.Some dermatologists now recommend using simple petrolatum on a minor cut to protect it. That avoids contact dermatitis due to an OTC topical antibiotic. Polymyxin and bacitracin, the other ingredients in Neosporin, may also be capable of triggering a reaction ( Dermatologic Surgery, Aug., 2013 ). Rate this article. 4.3 - 174 rating s.Alternative if allergic to sulfonamides: Ease of application and of removal. Painless. Frequent dressing changes: Bacterial resistance. Allergic reaction. Signs of reepithelialization: Yeast colonization. Skin hypersensitivity. Ototoxicity and nephrotoxicity with neomycin-containing ointments (eg, Neosporin) Mupirocin ointment/cream 2%: Small ...risk of an allergic reaction after the subsequent receipt of a SNA was lower than the risk of an allergic reaction after the subsequent receipt of a penicillin (adjusted odds ratio, 0.7;A sulfa allergy occurs when a person has an allergic reaction to drugs that contain chemicals called sulfonamides. Symptoms may include a rash, difficulty breathing, and more. Sulfa is present in ...Apr 28, 2022 ... it contains a sulfa atom, but it is not a sulfonamide, in other words, no, it will not have sulfonamide cross reaction. no allergy. If you have ...Lanolin is a natural substance that has been used for centuries in various skincare and cosmetic products. Derived from sheep’s wool, lanolin offers numerous benefits for the skin,...The HSRs to tetracyclines, their workup, and management are described for 10 patients, aged 7 to 68 years. Our skin testing protocols for doxycycline, minocycline, and tigecycline described herein had good negative predictive value. When skin testing was negative and the initial reaction was not severe, graded challenge to the culprit drug was ... Neosporin sulfa allergy, Penicillin allergy is the most commonly reported drug allergy in the United States. Although penicillin allergy is widely reported, 80% to 90% of individuals with self-reported penicillin allergy are actually able to tolerate penicillins after undergoing evaluation for penicillin allergy. Because most patients with self-reported penicillin allergy will have subsequent negative allergy testing ..., Clean and thoroughly dry the area to be treated. Apply this medication to the affected skin, usually twice a day or as directed by your doctor. If you are using the spray form, shake the bottle ..., Neosporin is often referred to as triple antibiotic ointment, because it contains three separate antibiotics: neomycin, polymyxin B, and bacitracin. In some formulations, Neosporin also contains an additional drug for pain relief - pramoxine hydrogen chloride. Neosporin is used to treat minor cuts, abrasions, puncture wounds, and other wounds., Patients with documented allergy to sulfonamide antibiotics may be at increased risk of all drug-induced reactions that appear to be allergic in nature, irrespective of drug class. The term “sulfa-allergy” is misleading, restrictive, and should be avoided. Healthcare professionals should instead document the exact drug and the nature of the ..., Side Effects. Burning, stinging, swelling, irritation, redness, pimple -like bumps, tenderness, or flaking of the treated skin may occur. If any of these effects last or get worse, notify your ..., [24–26] Patients labelled as sulfa allergic could have had a reaction previously to sulphonamide antibiotics or a non-antibiotic sulphonamide, and notably there is no cross-reactivity between sulphonamide antibiotics and non-antibiotic sulphonamides. Sulphonamide antibiotics are implicated in benign T-cell-mediated rashes and SCARs., Takeaway. Despite having similar names and symptoms, sulfa and sulfite allergies are different. Sulfa refers to sulfonamides, known as sulfa drugs, while sulfite is commonly found in wine ..., Is polymyxin b trimethoprim opth eye drops a sulfa based drug? i have an allergy to sulfa drugs. A doctor has provided 1 answer. Dr. Nayla Mumneh answered. Specializes ... to polymixin b sulfate/trimethoprim opthalmic drops do fine with neosporin? A doctor has provided 1 answer. A member asked: Can someone with bactrim …, BAcitrAcin. Your patch test result indicates that you have a contact allergy to bacitracin. This contact allergy may cause your skin to react when it is exposed to this substance although it may take several days for the symptoms to appear. Typical symptoms include redness, swelling, itching, and fluid-filled blisters., Allergens like pollen, dust, pet dander and other environmental triggers can cause allergic conjunctivitis—a non-contagious form of pink eye that causes watery eyes, itching and burning., hearing loss; or. skin rash, redness, swelling, itching, dryness, scaling, or other irritation in or around the ear. Common side effects of hydrocortisone, neomycin, and polymyxin B otic may include: mild itching after using the ear drops. This is not a complete list of side effects and others may occur. Call your doctor for medical advice ..., General Chit-Chat (non-quilting talk) - Neosporin is a sulpha drug! - I learned a really important lesson, for me, this week! My dog bit me last Saturday evening when I had him at the groomers to be clipped. He was coming out of sedation, there was a commotion and he slipped the muzzle and bit me because I was holding, Signs of Wound Infection. Wound infection symptoms can start up to a month after you receive the initial wound. 5 Common signs of infection include: Redness 3 or dark streaks spreading around the cut 6. Hot to touch and tender skin 3. Swelling or pain 3. Blood or pus coming from the wound 3., Neosporin has an average rating of 6.5 out of 10 from a total of 2 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 50% reported a negative effect. Sulfamethoxazole / trimethoprim has an average rating of 4.9 out of 10 from a total of 1720 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 47% ..., October 14, 2023 by DR HARUN, DVM. Dogs can be allergic to Neosporin, a common topical antibiotic ointment often used for humans. However, it is always best to consult with a veterinarian before using any medication on your dog's skin to ensure their safety and well-being. Neosporin contains ingredients that can potentially cause an allergic ..., Abstract. Cephalosporins can cause a range of hypersensitivity reactions, including IgE-mediated, immediate reactions. Cephalosporin allergy has been reported with use of a specific cephalosporin, as a cross-reaction between different cephalosporins or as a cross-reaction to other β-lactam antibiotics. Unlike penicillins, the exact allergenic ..., Neosporin is potentially bad for tattoos because it sometimes causes an allergic reaction, according to About.com. This, in turn, can give a permanent “spotted” appearance to the t..., Options for treatment of mild to moderate nonpurulent infections include cefazolin, ceftriaxone, clindamycin, and penicillin [ 6 ]. Although there is a lack of data to support the optimal duration of antibiotic therapy, the guidelines recommend a treatment duration of 7-10 days [ 6 ]., FAQ. Neosporin is an antibacterial ointment that can help keep a cut from getting infected, but it should not be used on every type of open wound. Some wounds don't need an antibiotic and treating them with one can add to the risk of allergic reaction and antibiotic resistance. Other, deeper wounds may need care that antibiotic ointment doesn't ..., Much like Polysporin, Neosporin also has an added active pain-relieving agent, named pramoxine. This added ingredient works to relieve the pain associated with the injury being treated. 4. Preference of Use. When considering Polysporin vs Neosporin, the use of Polysporin is usually more advised due to the fact that there is a less likely chance ..., Skin tests. With a skin test, the allergist or nurse administers a small amount of a suspect drug to your skin either with a tiny needle that scratches the skin, an injection or a patch. A positive reaction to a test often causes a red, itchy, raised bump. A positive result suggests you may have a drug allergy., New research shows 20% of Americans believe they have a food allergy, but only 10% has actually been properly diagnosed. More than a fifth of American adults believe they have a fo..., Aug 3, 2015 · Some dermatologists now recommend using simple petrolatum on a minor cut to protect it. That avoids contact dermatitis due to an OTC topical antibiotic. Polymyxin and bacitracin, the other ingredients in Neosporin, may also be capable of triggering a reaction ( Dermatologic Surgery, Aug., 2013 ). Rate this article. 4.3 - 174 rating s. , Allergic reactions may be due to bacitracin or to irritation from or allergy to other components of the preparation, such as the antibacterial agent neomycin, which is known to be a potent sensitiser. Bacitracin allergy is confirmed by performing patch tests to bacitracin. The correct concentration is uncertain, ranging from 1% to 20% ... , INTRODUCTION. Methicillin resistance in Staphylococcus aureus (MRSA) is defined by the Clinical Laboratory Standards Institute (CLSI) as an oxacillin minimum inhibitory concentration (MIC) ≥4 mcg/mL [].According to the European Committee on Antimicrobial Susceptibility Testing (EUCAST), S. aureus with oxacillin MIC values >2 mg/L are mostly methicillin resistant []., Before applying the medication, clean the burned area and remove any dead or burned skin. Always wear a sterile, disposable glove when you apply silver sulfadiazine. Cover the cleaned burned area with a 1/16-inch (0.2-centimeter) thickness of cream. Keep the burned area covered with cream at all times; reapply the cream to any area that becomes ..., Some dermatologists now recommend using simple petrolatum on a minor cut to protect it. That avoids contact dermatitis due to an OTC topical antibiotic. Polymyxin and bacitracin, the other ingredients in Neosporin, may also be capable of triggering a reaction ( Dermatologic Surgery, Aug., 2013 ). Rate this article. 4.3 - 174 rating s., Neosporin Side Effects. Generic name: bacitracin / neomycin / polymyxin b topical Medically reviewed by Drugs.com. Last updated on Mar 29, 2023. Serious side effects; FAQ; Note: This document contains side effect information about bacitracin / neomycin / polymyxin b topical. Some dosage forms listed on this page may not apply to the brand name Neosporin., Specializes in Infectious Disease. Neither: I think you mean Macrobid (nitrofurantoin), which is neither a sulfa drug or a penicillin. Answered 6/27/2014. 4.9k views. Thank. Dr. George Klauber answered. Specializes in Pediatric Urology. Neither: Macrobid is Nitrofurantoin in longacting macrocrystal form. Has nothing to do with either sulfa or ..., Description for Cortisporin Otic Suspension. CORTISPORIN® Otic Suspension (neomycin and polymyxin B sulfates and hydrocortisone otic suspension, USP) is a sterile antibacterial and anti-inflammatory suspension for otic use. Each mL contains: neomycin sulfate equivalent to 3.5 mg neomycin base, polymyxin B sulfate equivalent to 10,000 polymyxin B units, and hydrocortisone 10 mg (1%)., Sulfa-based eye drops like Genoptic (gentamicin sulfate), Polytrim (polymyxin B/trimethoprim), atropine sulfate, and Maxitrol (neomycin/dexamethasone/polymyxin B) are safe to use in those with reported sulfa allergies. Can you use Neosporin If you have a sulfa allergy? No. None of the ingredients are sulfanomide (sulfa) antibiotics., 1,071 Posts. Specializes in School Nurse. May 31, 2018. Neosporin & triple antibiotic cream has sulfa in it so some students may have an allergic reaction. Soap & water is the standard for basic first aid. No crutches - parents provide. Cough drops are just not effective. JenTheSchoolRN, BSN, RN., If you're allergic to penicillin or sulfa antibiotics, Neosporin Plus Pain Relief ointment is safe for you to use since the formula in this medication doesn't contain either type of antibiotic. But if you're allergic to medications such as gentamicin (Gentak) , streptomycin, and paromomycin , talk to your provider first before using Neosporin ...